Necrotizing sarcoid granulomatosis: ocular manifestation in 3 children of African origin.

Necrotizing sarcoid granulomatosis (NSG) is a rare systemic disease characterized by confluent sarcoidlike granulomas with necrotic areas and a variable degree of vasculitis. First described by Liebow in 1973, NSG can be classified as a disease showing features of Wegener granulomatosis and sarcoidosis. The etiology and pathogenesis of NSG are so far unknown; it is considered to be unrelated to infection. Necrotizing sarcoid granulomatosis is an extremely rare disease in childhood, with only a few cases reported to date. In this case report, we describe 3 children of African origin who were diagnosed with an ocular manifestation of NSG.